Title :
An investigative study of membrane-based biosensors
Author :
Lader, Alan S. ; Tamanaha, Cy ; Li, Jianguo ; Downer, Nancy W. ; Smith, H.G. ; Mendelson, Yitzhak ; Peura, Robert A.
Author_Institution :
Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA
Abstract :
A system for incorporating naturally occurring membrane-based biological recognition elements into surface structures has been investigated. Alkylsilane molecules were covalently bound to the surface of a silicon/silicon dioxide (Si/SiO2) electrode as one half of a bilayer membrane mimetic structure. Detergent dialysis was then used to reconstitute lipids and proteins into the other half of this structure
Keywords :
biomedical equipment; biomembranes; biosensors; Si-SiO2 electrode; alkylsilane molecules; biological recognition elements; detergent dialysis; lipids; membrane-based biosensors; proteins; surface structures; Biomedical engineering; Biomembranes; Biosensors; Capacitance measurement; Electrodes; Kirchhoff´s Law; Microorganisms; Optical surface waves; Proteins; Silicon;
Conference_Titel :
Bioengineering Conference, 1991., Proceedings of the 1991 IEEE Seventeenth Annual Northeast
Conference_Location :
Hartford, CT
Print_ISBN :
0-7803-0030-0
DOI :
10.1109/NEBC.1991.154670
