• DocumentCode
    2609508
  • Title

    An investigative study of membrane-based biosensors

  • Author

    Lader, Alan S. ; Tamanaha, Cy ; Li, Jianguo ; Downer, Nancy W. ; Smith, H.G. ; Mendelson, Yitzhak ; Peura, Robert A.

  • Author_Institution
    Dept. of Biomed. Eng., Worcester Polytech. Inst., MA, USA
  • fYear
    1991
  • fDate
    4-5 Apr 1991
  • Firstpage
    253
  • Lastpage
    254
  • Abstract
    A system for incorporating naturally occurring membrane-based biological recognition elements into surface structures has been investigated. Alkylsilane molecules were covalently bound to the surface of a silicon/silicon dioxide (Si/SiO2) electrode as one half of a bilayer membrane mimetic structure. Detergent dialysis was then used to reconstitute lipids and proteins into the other half of this structure
  • Keywords
    biomedical equipment; biomembranes; biosensors; Si-SiO2 electrode; alkylsilane molecules; biological recognition elements; detergent dialysis; lipids; membrane-based biosensors; proteins; surface structures; Biomedical engineering; Biomembranes; Biosensors; Capacitance measurement; Electrodes; Kirchhoff´s Law; Microorganisms; Optical surface waves; Proteins; Silicon;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference, 1991., Proceedings of the 1991 IEEE Seventeenth Annual Northeast
  • Conference_Location
    Hartford, CT
  • Print_ISBN
    0-7803-0030-0
  • Type

    conf

  • DOI
    10.1109/NEBC.1991.154670
  • Filename
    154670