Title :
Boundary element analysis of the electrostatic interactions between organic scaffolds and transmembrane proteins
Author :
Ansalone, D.P. ; Bottauscio, O. ; Manzin, A.
Author_Institution :
Ist. Naz. di Ricerca Metrologica (INRIM), Torino, Italy
Abstract :
This paper investigates the electrostatic interactions between organic scaffolds and the transmembrane proteins involved in cell adhesion. The analysis is performed through the solution of the linearized Poisson-Boltzmann equation by means of the Boundary Element Method. The electrostatic energy is evaluated varying the relative position of the interacting molecules and the properties of the solvent.
Keywords :
Boltzmann equation; Poisson equation; biomembranes; boundary-elements methods; cellular biophysics; electrostatics; molecular biophysics; proteins; tissue engineering; boundary element method; cell adhesion; electrostatic energy; electrostatic interactions; linearized Poisson-Boltzmann equation; organic scaffolds; transmembrane proteins; Adhesives; Boundary element methods; Cells (biology); Dielectric constant; Electrostatic analysis; Molecular biophysics; Performance analysis; Poisson equations; Proteins; Solvents;
Conference_Titel :
Electromagnetic Field Computation (CEFC), 2010 14th Biennial IEEE Conference on
Conference_Location :
Chicago, IL
Print_ISBN :
978-1-4244-7059-4
DOI :
10.1109/CEFC.2010.5481482
