Title :
The optimal Design of Electrod Array using Electroporation Based on the Finite Element
Author :
Dong-yang, Zhao ; Cheng-xiang, Li ; Yan, Mi ; Chen-guo, Yao
Author_Institution :
State Key Lab. of Power Transm. Equip. & Syst. Security & New Technol., Chongqing
Abstract :
With the promotion of the electroporation therapy clinical application, how to design an electrode with a lower voltage level and distribution and high intensity electric field in order to achieve the optimal treatment of tumors. In this paper, FEMLAB finite element analysis software is used for the needle electrodes in biological tissue electroporation for electric field simulation, the simulation results show that: voltage amplitude, the distance between positive and negative electrode needle, needle electrodes and the number of needle electrodes, and other distribution methods will affect the effective electric field area of biological tissue. By comparing different needle electrodes corresponds to the structure of the electric field distribution uniformity, the effective electric field (Eeff) radius of coverage as well as the size of the rated output voltage power supply requirements, We has designed optimal structure of the needle electrodes (seven plum blossom-shaped electrodes acupuncture), which provide a theoretical basis for the production of needle electrodes.
Keywords :
biological effects of fields; finite element analysis; medical computing; tumours; FEMLAB finite element analysis software; biological tissue electroporation; electric field distribution corresponds; electric field simulation; electrod array design; electroporation therapy clinical application; negative electrode needle; positive electrode needle; tumors optimal treatment; Analytical models; Application software; Biological system modeling; Biological tissues; Electrodes; Finite element methods; Medical treatment; Needles; Neoplasms; Voltage; FEMLAB; electric field calculation; electroporation; electroporation electrode;
Conference_Titel :
High Voltage Engineering and Application, 2008. ICHVE 2008. International Conference on
Conference_Location :
Chongqing
Print_ISBN :
978-1-4244-3823-5
Electronic_ISBN :
978-1-4244-2810-6
DOI :
10.1109/ICHVE.2008.4774048