DocumentCode
2614235
Title
A noise mechanism for model observers
Author
Pereira, Nicholas F. ; Gifford, Howard C. ; King, Michael A.
Author_Institution
Nuclear Medicine Physics Laboratory, Brigham and Women¿s Hospital, Boston, MA 02130 USA
fYear
2008
fDate
19-25 Oct. 2008
Firstpage
4433
Lastpage
4439
Abstract
Model observers may be employed as surrogates for human observers for various parameter optimization tasks that involve evaluation of imaging systems and processing algorithms. For a lesion localization-detection task, model observers based on statistical detection theory typically demonstrates superior performance compared to human observers. Inclusion of an internal-noise-mechanism can allow a model observer to better match humans. In a sequential reading task, human-observer internal noise may depend in a complicated manner on the ensemble of image data in addition to the particular image being viewed in the sequence. There may be other data-independent components of internal-noise as well. In this work, we propose an internal-noise model that takes this conditional dependence on the data-ensemble into consideration. Different ways of defining the ensemble lead to different sets of parameters for the noise-model, which in turn lead to different dynamics for the parameter-optimization curves. We explore these various cases using the channelized non-prewhitening (CNPW) observer. Our dataset consisted of Ga-67 hybrid SPECT/CT data, which was reconstructed using various combinations of attenuation compensation (AC), scatter Compensation (SC) and resolution compensation (RC). We generate optimization curves for these different combinations and compare the results with the noise-less case.
Keywords
Attenuation; Biomedical imaging; Humans; Image reconstruction; Lesions; Noise generators; Nuclear medicine; Physics; Scattering; Vectors; CNPW; Hybrid data; RBI-EM; internal noise; kernel density estimator; model observer; sigmoid function;
fLanguage
English
Publisher
ieee
Conference_Titel
Nuclear Science Symposium Conference Record, 2008. NSS '08. IEEE
Conference_Location
Dresden, Germany
ISSN
1095-7863
Print_ISBN
978-1-4244-2714-7
Electronic_ISBN
1095-7863
Type
conf
DOI
10.1109/NSSMIC.2008.4774266
Filename
4774266
Link To Document