• DocumentCode
    2614235
  • Title

    A noise mechanism for model observers

  • Author

    Pereira, Nicholas F. ; Gifford, Howard C. ; King, Michael A.

  • Author_Institution
    Nuclear Medicine Physics Laboratory, Brigham and Women¿s Hospital, Boston, MA 02130 USA
  • fYear
    2008
  • fDate
    19-25 Oct. 2008
  • Firstpage
    4433
  • Lastpage
    4439
  • Abstract
    Model observers may be employed as surrogates for human observers for various parameter optimization tasks that involve evaluation of imaging systems and processing algorithms. For a lesion localization-detection task, model observers based on statistical detection theory typically demonstrates superior performance compared to human observers. Inclusion of an internal-noise-mechanism can allow a model observer to better match humans. In a sequential reading task, human-observer internal noise may depend in a complicated manner on the ensemble of image data in addition to the particular image being viewed in the sequence. There may be other data-independent components of internal-noise as well. In this work, we propose an internal-noise model that takes this conditional dependence on the data-ensemble into consideration. Different ways of defining the ensemble lead to different sets of parameters for the noise-model, which in turn lead to different dynamics for the parameter-optimization curves. We explore these various cases using the channelized non-prewhitening (CNPW) observer. Our dataset consisted of Ga-67 hybrid SPECT/CT data, which was reconstructed using various combinations of attenuation compensation (AC), scatter Compensation (SC) and resolution compensation (RC). We generate optimization curves for these different combinations and compare the results with the noise-less case.
  • Keywords
    Attenuation; Biomedical imaging; Humans; Image reconstruction; Lesions; Noise generators; Nuclear medicine; Physics; Scattering; Vectors; CNPW; Hybrid data; RBI-EM; internal noise; kernel density estimator; model observer; sigmoid function;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Nuclear Science Symposium Conference Record, 2008. NSS '08. IEEE
  • Conference_Location
    Dresden, Germany
  • ISSN
    1095-7863
  • Print_ISBN
    978-1-4244-2714-7
  • Electronic_ISBN
    1095-7863
  • Type

    conf

  • DOI
    10.1109/NSSMIC.2008.4774266
  • Filename
    4774266