Title :
Čerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip
Author :
Cho, LS ; Douraghy, A. ; Olma, S. ; Liu, K. ; Chen, Y.C. ; Shen, C.K. ; Silverman, R.W. ; van Dam, R.M. ; Chatziioannou, Arion F.
Author_Institution :
UCLA School of Medicine, Department of Pharmacology, Crump Institute at 700 Westwood Plaza, Los Angeles, CA, 90095-1770, USA
Abstract :
This work proposes a novel method for quantitative imaging of radioactivity on microfluidic chips by using visible light emission from Čerenkov radiation. Čerenkov radiation is generated when charged particles travel through an optically transparent material with a velocity greater than that of light in that material. It has been observed at UCLA that microfluidic chips used for 18F-related radio-synthesis studies have shown unidentified visible light emissions. In this study, the origin of the light was investigated and its feasibility as a quantitative imaging source was tested.
Keywords :
Beta rays; Microfluidics; Optical imaging; Optical materials; Particle measurements; Radiation imaging; Radioactive materials; Semiconductor device measurement; Stimulated emission; Testing; Čerenkov radiation; Beta particles; charged coupled device (CCD); microfluidic chips;
Conference_Titel :
Nuclear Science Symposium Conference Record, 2008. NSS '08. IEEE
Conference_Location :
Dresden, Germany
Print_ISBN :
978-1-4244-2714-7
Electronic_ISBN :
1095-7863
DOI :
10.1109/NSSMIC.2008.4774293
