Modelling and identification of in vitro homoacetogenesis by human-colon bacteria

A nonlinear ODE model for in vitro homoacetogenesis by human-colon bacteria is proposed and analysed. This model takes into account the biological and physical features of the experiment under consideration and the measurement process. An identifiability analysis is carried out, and the parameters of the model are identified using four different statistical description of the errors on the measurements. The estimated values will be used as prior estimates in a more ambitious modelling project of the carbohydrate trophic chain in the human colon.