Title :
Multi-functional biochip for biological agent detection
Author :
Vo-Dinh, Tuan ; Griffin, Guy D. ; Wintenberg, Alan L. ; Stokes, David T. ; Stratis, Dimitra ; Mobley, Joel ; Maples, Robert
Author_Institution :
Oak Ridge Nat. Lab., TN, USA
Abstract :
Multifunctional biochip (MFB) is a unique system that allows simultaneous detection of multiple biotargets simultaneously. The MFB is an integrated multi-array biochip, which is designed by combining integrated circuit elements, an electro-optics excitation/detection system, and bioreceptor probes into a self-contained and integrated microdevice. The multi-functional capability of MFB is demonstrated using the biochip as both an antibody-based and DNA sensor. The study indicates that the biochip technology provides an important tool to warn of exposure to pathogenic agents for use in human health protection and homeland defense.
Keywords :
DNA; biomedical equipment; biomolecular electronics; biosensors; biotechnology; microfluidics; microorganisms; molecular biophysics; patient care; DNA sensor; antibody based sensor; biochip technology; biological agent detection; bioreceptor probes; biotargets; electrooptics excitation-detection system; homeland defense; human health protection; multiarray biochip; multifunctional biochip; pathogenic agents; Biosensors; DNA; Electronic mail; Genetic mutations; Immune system; Laboratories; Organisms; Pathogens; Probes; Sampling methods;
Conference_Titel :
Semiconductor Device Research Symposium, 2003 International
Print_ISBN :
0-7803-8139-4
DOI :
10.1109/ISDRS.2003.1272222