DocumentCode
262059
Title
Central Dogma of Molecular Biology - New Paradigm in Evolutionary Computation
Author
Rotar, Corina
Author_Institution
Comput. Sci. Dept., “1 Decembrie 1918” Univ., Alba Iulia, Romania
fYear
2014
fDate
22-25 Sept. 2014
Firstpage
285
Lastpage
292
Abstract
The aim of this study is to develop a new evolutionary computation paradigm in terms of molecular biology. Standard genetic algorithms are heuristics inspired by the simplified model of natural evolution and genetics. The latest discoveries and innovations from molecular biology, related to the conventional central dogma of molecular biology, generate the necessity of updating the genetic algorithms, although successfully applied in various complex tasks. In this direction, the research in Evolutionary Computation requires a reconsideration of the concepts and theories underlying the development of these popular optimization techniques. Since the emergence of the new features is important in the evolution, the DNA code requires progress. Evolutionary Computation which is based on the mutation and the natural selection can be reconsidered in terms of protein synthesis and reverse transcription. From the computational perspective, a biological phenomenon might be interpreted in various forms in order to obtain reliable computational techniques.
Keywords
DNA; RNA; bioinformatics; genetic algorithms; molecular biophysics; proteins; DNA code; biological phenomenon; central dogma; complex tasks; computational perspective; computational techniques; evolutionary computation paradigm; heuristics; molecular biology; mutation; natural selection; protein synthesis; reverse transcription; simplified genetic model; simplified natural evolution model; standard genetic algorithm update; DNA; Evolution (biology); Optimization; Proteins; RNA; central dogma of biology; evolutionary computation paradigm; optimization; protein synthesis;
fLanguage
English
Publisher
ieee
Conference_Titel
Symbolic and Numeric Algorithms for Scientific Computing (SYNASC), 2014 16th International Symposium on
Conference_Location
Timisoara
Print_ISBN
978-1-4799-8447-3
Type
conf
DOI
10.1109/SYNASC.2014.46
Filename
7034696
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