Radiation exposure facilities for medical studies in vitro and vivo

This paper presents several radiation exposure facilities (REFs) which permit separate and simultaneous irradiation with microwaves (MW) of 2.45 GHz and electron beams (EB) of 6.23 MeV for medical studies in vitro and vivo. These REFs are special designed for the following medical studies and applications: 1) The effects of separate MW exposure on the B16F10 mouse malignant melanoma (MM) cells culture without/ with dacarbazine incubation; 2) The effects of combined MW and EB irradiation on the B16F10 mouse MM cell cultures; 3) The effects of combined MW and EB irradiation on human blood components (proteins and cells) irradiated in samples of integral blood from healthy donors and from donors with MM; 4) The effects of combined MW and EB whole body irradiation on the C57BL/6 mice bearing MM without/with drugs (dacarbazine or bleomycin) administration; 5) Preparation of a new commercial vaccine designed for prophylaxis of ruminant infectious pododermatitis produced by Fusobacterium necrophorum gram negative bacteria.