Computational aspects of MN activity estimation: A case study with post-stroke subjects

Spinal circuits play an important role in the generation of rhythmic motor activity, intermediating between descending signals and peripheral sensory information. The study of these circuits can provide a better understanding of the control mechanisms during the execution of cyclic motor tasks in healthy subjects or in patients with motor deficits due to a neurological disease. This work shows preliminary results regarding the estimation of spinal cord activity of post-stroke subjects obtained from the EMG signals by improving the computational model. This new model allows a better quantitative evaluation of motor performance in clinical contexts.