Title :
Visualizing a Correlative Multi-level Graph of Biology Entity Interactions
Author :
You, Qian ; Fang, Shiaofen ; Mukhopadhyay, Snehasis ; Vaka, Harsha Gopal Goud ; Chen, Jake
Author_Institution :
Sch. of Sci., Dept. of Comput. & Inf. Sci., Purdue Univ., Indianapolis, IN, USA
Abstract :
In this paper we present a new visualization paradigm to represent and assist the understanding of a correlative multi-level graph, a group of interconnected networks. Such a graph is formed via term association mining, and the visualization paradigm consists of three components: terrain surface visualization units, terrain surface arrangement, and terrain surface correlation. We apply this paradigm to visualize and explore a pair of correlative core cancer terms network and core gene terms network. The results show that our visualization paradigm design is consistent with the derived associations, and is effective in preserving major features as the landmarks in the terrain surfaces.
Keywords :
biology computing; cancer; data mining; data visualisation; genetics; graph theory; biology entity interactions; core gene terms network; correlative core cancer terms network; correlative multilevel graph; interconnected networks; term association mining; terrain surface arrangement; terrain surface correlation; terrain surface visualization units; visualization paradigm; Bioinformatics; Biological information theory; Cancer; Data visualization; Intelligent networks; Large-scale systems; Scalability; Surface treatment; Systematics; Systems biology;
Conference_Titel :
Network-Based Information Systems, 2009. NBIS '09. International Conference on
Conference_Location :
Indianapolis, IN
Print_ISBN :
978-1-4244-4746-6
Electronic_ISBN :
978-0-7695-3767-2
DOI :
10.1109/NBiS.2009.37