Title :
Triple quantum filtered sodium MRI of primary brain tumors
Author :
Boada, F.E. ; Davis, D. ; Walter, K. ; Torres-Trejo, A. ; Kondziolka, D. ; Bartynski, W. ; Lieberman, F.
Author_Institution :
Pittsburgh Univ., PA, USA
Abstract :
We demonstrate the use of triple quantum (TQ) filtered sodium MRI for the monitoring of primary brain tumors. The TQ images were acquired using a twisted-projection readout in tandem with a three-pulse triple quantum filter. Our results demonstrate that TQ sodium MRI provides a source of contrast that it is not biased by the large sodium content of the extracellular pool and is, therefore, better suited for monitoring the changes in intracellular sodium content associated with the development of neoplastic changes.
Keywords :
biochemistry; biomedical MRI; brain; cancer; cellular biophysics; patient monitoring; sodium; tumours; Na; extracellular sodium; image acquisition; intracellular sodium content; neoplastic changes; primary brain tumors monitoring; three-pulse triple quantum filter; triple quantum filtered sodium MRI; twisted-projection readout; Biological tissues; Biopsy; Cancer; Cells (biology); Extracellular; Magnetic resonance imaging; Medical treatment; Monitoring; Neoplasms; Nuclear magnetic resonance;
Conference_Titel :
Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on
Print_ISBN :
0-7803-8388-5
DOI :
10.1109/ISBI.2004.1398763
