Title :
Cell-based screening for function
Author :
Shay, Tal ; Naffar-Abu-Amara, Suha ; Paran, Yael ; Zamir, Eli ; Liron, Yuvalal ; Geiger, Benjamin ; Kam, Zvi
Author_Institution :
Dept. of Molecular Cell Biol., Weizmann Inst. of Sci., Rehovot, Israel
Abstract :
Biological image analysis software packages offer tools to analyze microscope images of cells. Some of these tools allow quantitative analysis through interactive processing. High-throughput applications employing microscopy for cell-based assays require analysis of large number of images. We describe here acquisition and analysis of cell images in high throughput automated mode aiming to screen for effects in structure and molecular organization of cellular components recorded by high resolution cell images and in cell motility.
Keywords :
biological techniques; biology computing; cell motility; image processing; biological image analysis; cell image acquisition; cell motility; cell structure; cell-based assays; cell-based screening; high resolution cell images; high throughput automated mode; microscopy; molecular organization; software package; Adhesives; Bioinformatics; Biological cells; Cells (biology); Cellular networks; Genetics; Genomics; Image analysis; Microscopy; Proteins;
Conference_Titel :
Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on
Print_ISBN :
0-7803-8388-5
DOI :
10.1109/ISBI.2004.1398770
