Traveling wave bio-agent concentrator

Author

Lean, Meng H. ; Völkel, Armin R. ; Hsieh, H.B. ; Lu, Jeng-P ; Daniel, Jürgen H. ; Preas, Bryan T. ; Limb, Scott J.

Author_Institution

Palo Alto Res. Center, CA, USA

fYear

2005

fDate

12-15 May 2005

Firstpage

80

Lastpage

83

Abstract

This paper describes a hybrid bio-agent concentrator device based on the combined performance of a modified field flow fractionation system for particulate deposition and a traveling wave transport mechanism to deliver and concentrate particulates into a sample well. The device has been successfully tested on B. thurengiensis and polystyrene beads in the threat range of 1-10 μm. This MEMS device may increase the concentration of post-ultrafiltration retentates or post-aerosol collected hydrosols by another 100X. As a front-end to detection, it will enhance the effective sensitivity of the detector. The device may also have bio medical implications in bio separation and cell enrichment.

Keywords

biological techniques; electrostatic devices; fractionation; micromechanical devices; microorganisms; B. thurengiensis; MEMS device; biomedical implication; bioseparation; cell enrichment; detector sensitivity; field flow fractionation system; hydrosols; particulate deposition; polystyrene beads; post-aerosol collection; post-ultrafiltration retentation; traveling wave bio-agent concentrator; traveling wave transport mechanism; Aerosols; Detectors; Electrodes; Electrostatics; Fabrication; Field-flow fractionation; Microelectromechanical devices; Phased arrays; Testing; Voltage;

fLanguage

English

Publisher

ieee

Conference_Titel

Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on

Print_ISBN

0-7803-8711-2

Type

conf

DOI

10.1109/MMB.2005.1548389

Filename

1548389