• DocumentCode
    2639480
  • Title

    A low power, polyimide valved micropump for precision drug delivery

  • Author

    Mercanzini, A. ; Bachmann, Michael ; Jordan, A. ; de Rooij, Nico ; Stergiopulos, Nikolaos

  • Author_Institution
    Lab. of Hemodynamics & Cardiovascular Technol., Swiss Fed. Inst. of Technol., Lausanne, Switzerland
  • fYear
    2005
  • fDate
    12-15 May 2005
  • Firstpage
    146
  • Lastpage
    149
  • Abstract
    We present a microfabricated pump designed for low flow-rate, implantable drug infusion. The positive displacement type micropump is actuated by a precision linear stepper fabricated using watch-making technology and incorporates two polyimide check-valves which were fabricated using photolithography. Two check-valve die are juxtaposed, bonded and subsequently packaged using PDMS bonding techniques. The design was implemented in order to meet the three major challenges that still face implantable micropumps; low power actuation, debris tolerant valves, and packaging.
  • Keywords
    drug delivery systems; micropumps; photolithography; PDMS bonding technique; drug delivery microfabricated pump design; implantable drug infusion; implantable micropump; photolithography; polyimide valved micropump; precision linear stepper fabrication; watch-making technology; Bonding; Drug delivery; Energy consumption; Hydraulic actuators; Micromechanical devices; Micropumps; Packaging; Pharmaceutical technology; Polyimides; Valves;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on
  • Print_ISBN
    0-7803-8711-2
  • Type

    conf

  • DOI
    10.1109/MMB.2005.1548408
  • Filename
    1548408