A magnetohydrodynamic (MHD) microfluidic platform for cell switching

Author

Wang, Lisen ; Flanagan, Lisa ; Monuki, Edwin ; Jeon, Noo Li ; Lee, Abraham P.

Author_Institution

Dept. of Biomed. Eng., California Univ., Irvine, CA, USA

fYear

2005

fDate

12-15 May 2005

Firstpage

276

Lastpage

279

Abstract

We present for the first time the demonstration of magnetohydrodynamic (MHD) micropump based microfluidic platform for cell switching. MHD micropumps were fabricated with a novel microfabrication process that can make vertical electrodes embedded inside microchannels to provide higher efficiency of pumping of the fluid. Multiple micropumps can be integrated on the same platform to have switching function for cell sorting. We have successfully demonstrated the pumping of two types of cells: mouse neural stem cells and neuroblastoma cells.

Keywords

biomedical electrodes; cellular biophysics; magnetohydrodynamics; microelectrodes; microfluidics; micropumps; neurophysiology; MHD micropump; cell sorting; cell switching; magnetohydrodynamic microfluidic platform; microchannel; microfabrication process; mouse neural stem cell; neuroblastoma cell; vertical electrode; Electrodes; Magnetic switching; Magnetohydrodynamics; Mice; Microchannel; Microfluidics; Micropumps; Pumps; Sorting; Stem cells; Cell sorting; Magnetohydrodynamic(MHD); Microfluidics;

fLanguage

English

Publisher

ieee

Conference_Titel

Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on

Print_ISBN

0-7803-8711-2

Type

conf

DOI

10.1109/MMB.2005.1548447

Filename

1548447