DocumentCode
2641699
Title
Scouting for imprecise temporal associations to support effectiveness of drugs during clinical trials
Author
Vincenti, Giovanni ; Hammell, Robert J., II ; Trajkovski, Goran
Author_Institution
Dept. of Comput. & Inf. Sci., Towson Univ., MD, USA
fYear
2005
fDate
26-28 June 2005
Firstpage
171
Lastpage
176
Abstract
The field of data mining is dedicated to the analysis of data to find underlying connections and the discovery of new patterns. This research targets the analysis of imprecise temporal associations through the modification of a standard market basket analysis approach by means of fuzzy set relations to classify the associations among different sources of data. The domain that is taken into consideration in this work is the one of medicine. We used data recorded within an Intensive Care Unit from a 8 month old infant that suffers from Acute Respiratory Distress Syndrome. In particular, we analyzed the response of the partial pressure of oxygen within the bloodstream to the application of a respirator. The results of this research show that it is possible to investigate such relations with the help of fuzzy set classification for temporal associations, and the result of such exploration is as easily understandable as the standard Market Basket algorithm. The findings support the physiological response, suggesting that this approach is worthy of notice. We are confident that such an algorithm will show its capabilities when applied to the clinical trials part of drug testing, given the results outlined in this article.
Keywords
data mining; drugs; fuzzy set theory; medical information systems; patient treatment; clinical trials; data mining; drug effectiveness; fuzzy set relation; imprecise temporal association; market basket analysis; medical informatics; pattern discovery; Algorithm design and analysis; Clinical trials; Clustering algorithms; Data analysis; Data mining; Drugs; Fuzzy sets; Pattern analysis; Pediatrics; Testing; Data mining; a-priori algorithm; market-basket algorithm; medical informatics; temporal associations;
fLanguage
English
Publisher
ieee
Conference_Titel
Fuzzy Information Processing Society, 2005. NAFIPS 2005. Annual Meeting of the North American
Print_ISBN
0-7803-9187-X
Type
conf
DOI
10.1109/NAFIPS.2005.1548528
Filename
1548528
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