The Logic of Hypothesis Generation in Kinetic Modeling of System Biology

In the past decades a lot of researches have been conducted to investigate pathways in order to increase the understanding of the mechanisms responsible for diseases and thus to find new treatments. One strategy to achieve this goal would be to inhibit or to trigger a part of the pathway that produces the disease. A strategy would be to first identify the pathway whose activity contributes to the disease and then look for drugs that inhibit or trigger the pathway acting on its internal components and reactions.