Title :
Nanostructured substrates for SERS detection of serotonin to indicate heart transplant rejection
Author :
Cheng, Y.-H. ; Achiam, Y. ; Chang, C. ; Rosfjord, K.M.
Author_Institution :
Univ. of Maryland, College Park
Abstract :
We will present nanostructured substrates designed for SERS detection of serotonin. These substrates are patterned with a combination of electron-beam lithography using hydrogen silsesquioxane resist and the wet deposition of gold colloids to insure repeatability and reliability while achieving the enhancement factor required for serotonin detection. The fabrication process and initial results will be presented.
Keywords :
cardiology; colloids; electron beam lithography; nanostructured materials; prosthetics; surface enhanced Raman scattering; SERS detection; electron-beam lithography; enhancement factor; fabrication process; gold colloids; heart transplant rejection; hydrogen silsesquioxane resist; nanostructured substrates; serotonin detection; wet deposition; Biology; Biomedical engineering; Biomedical optical imaging; Educational institutions; Heart; Nanobioscience; Optical scattering; Physics; Raman scattering; Spectroscopy;
Conference_Titel :
Semiconductor Device Research Symposium, 2007 International
Conference_Location :
College Park, MD
Print_ISBN :
978-1-4244-1892-3
Electronic_ISBN :
978-1-4244-1892-3
DOI :
10.1109/ISDRS.2007.4422315
