Title :
Nanostructured CMOS wireless ultra-wideband label-free DNA analysis SoC
Author :
Jafari, H.M. ; Soleymani, L. ; Abdelhalim, K. ; Sargent, E.H. ; Kelley, S.O. ; Genov, R.
Author_Institution :
Univ. of Toronto, Toronto, ON, Canada
Abstract :
A 0.13-micron CMOS fully integrated 48-channel UWB label-free DNA analysis SoC is demonstrated in prostate cancer screening. The 3mm×3mm die includes 578 nanostructured DNA sensors, 48 pH sensors, and 48 temperature sensors and reuses key circuits for cyclic voltammetry, amperometry and temperature regulation.
Keywords :
CMOS integrated circuits; DNA; biomedical electronics; biosensors; cancer; prosthetics; system-on-chip; ultra wideband technology; SoC UWB label-free DNA analysis; amperometry; cyclic voltammetry; nanostructured CMOS SoC DNA analysis; nanostructured DNA sensors; pH sensors; prostate cancer screening; size 0.13 micron; temperature regulation; temperature sensors; wireless ultra-wideband label-free DNA analysis SoC; Clocks; DNA; Electrodes; Gold; Random access memory; Temperature sensors;
Conference_Titel :
VLSI Circuits (VLSIC), 2012 Symposium on
Conference_Location :
Honolulu, HI
Print_ISBN :
978-1-4673-0848-9
Electronic_ISBN :
978-1-4673-0845-8
DOI :
10.1109/VLSIC.2012.6243820
