Title :
Scalable low cost architecture for analysis of Lab-on-Chip data
Author :
Blionas, Spyridon
Author_Institution :
Dept. of Sci. & Technol. of Telecommun., Univ. of Peloponnese, Tripolis, Greece
Abstract :
This paper presents an architecture of the data processing (analysis) part, of a Lab-on-Chip (LoC) device. The LoC is a heterogeneous device accommodating mechanical, microsystems and electronics sections. Biological reactions are performed in the microfluidics part of the device, then the biological process results are detected by the Microsystems part and finally the electronics section handles the readout and the data processing for presenting the results to the final user for decision making. The micro-system part is an array of sensors for hybridization electronic detection; the readout is a mixed digital-analogue circuitry for converting the sensors measurements to digital data and the processing part for the data analysis may be an efficient hardware architecture for processing the data in real-time. LoCs are used for molecular Diagnostics or Pharmacogenomics applications, identifying the existence of particular DNA mutations or antibodies into the sample under examination.
Keywords :
biochemistry; data analysis; decision making; lab-on-a-chip; microfluidics; microsensors; mixed analogue-digital integrated circuits; molecular biophysics; sensor arrays; DNA mutation; biological reaction; data processing architecture; decision making; heterogeneous device; hybridization electronic detection; lab-on-chip data analysis; microfluidics; microsystem; mixed digital-analogue circuitry; molecular diagnostics; pharmacogenomics application; sensor array; Artificial neural networks; Biology; Biosensors; Biotechnology; Lab-on-Chip; System architecture;
Conference_Titel :
Electronics, Circuits, and Systems (ICECS), 2010 17th IEEE International Conference on
Conference_Location :
Athens
Print_ISBN :
978-1-4244-8155-2
DOI :
10.1109/ICECS.2010.5724574