Title :
Time-course analysis of tablet film-coating using terahertz pulsed imaging
Author :
Sakamoto, Tomoaki ; Nakayama, Koji ; Portieri, Alessia ; Arnone, Donald D. ; Sasakura, Daisuke ; Taday, Philip F. ; Zeitler, A. ; Kawanishi, Toru ; Hiyama, Yukio
Author_Institution :
Div. of Drugs, Nat. Inst. of Health Sci., Tokyo, Japan
Abstract :
Quality attribute of tablet coating on a film-coating process was investigated by a terahertz pulsed imaging. The time-dependent change of intensities of reflex THz pulse and coating layer thicknesses were compared. The forming of coating layer was observed at 30 min after the process was started.
Keywords :
drugs; nondestructive testing; pharmaceutical technology; protective coatings; quality control; terahertz wave imaging; coating layer thicknesses; quality attributes; tablet film coating; terahertz pulsed imaging; time course analysis; Coatings; Embossing; Imaging; Pharmaceuticals; Process control; Surface treatment; Time domain analysis;
Conference_Titel :
Infrared, Millimeter and Terahertz Waves (IRMMW-THz), 2011 36th International Conference on
Conference_Location :
Houston, TX
Print_ISBN :
978-1-4577-0510-6
Electronic_ISBN :
2162-2027
DOI :
10.1109/irmmw-THz.2011.6105249
