DocumentCode
2679544
Title
ISCOMATRIX Application of Nanotechnology
Author
Yao, Peng ; Jian, An
Author_Institution
Animal Sci. & Technol. Coll., Beijing Agric. Coll., Beijing, China
fYear
2012
fDate
28-30 May 2012
Firstpage
340
Lastpage
343
Abstract
Immunostimulatory complexes (ISCOMs), composed of antigen, saponin, cholesterol, and phospholipid, are the typical nano materials. It has the ability to hold antigen to delivery system, while ISCOMATRIX is a particulate adjuvant comprising saponin, cholesterol and phospholipid but antigen absence. The misture of antigens with ISCOMATRIX is called an ISCOMATRIX vaccine. In this paper, a new material (DC-Chol) to form ISCOMATRIX by the method of dialysis. The ISCOMATRIX is a nano materials and have the targenting effect. It has the advantage of taking the antigen to targeting cell(APCs).
Keywords
biomedical materials; drug delivery systems; drugs; molecular biophysics; nanomedicine; nanostructured materials; DC-Chol material; ISCOMATRIX vaccine; antigen; cholesterol; delivery system; dialysis; immunostimulatory complex; nanomaterials; nanotechnology; phospholipid; saponin; Animals; Educational institutions; Immune system; Nanobioscience; Nanostructured materials; Vaccines; DC-Chol; ISCOMATRIX; Nano-materials;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
Conference_Location
Macau, Macao
Print_ISBN
978-1-4577-1987-5
Type
conf
DOI
10.1109/iCBEB.2012.256
Filename
6245124
Link To Document