Title :
The Research on Synthesis Methods of Anticoagulants
Author :
Ren, Yujie ; Du, Cheng
Author_Institution :
Sch. of Chem. & Environ. Eng., Shanghai Inst. of Technol., Shanghai, China
Abstract :
This paper summarizes existing anticoagulants mainly from synthesis methods perspective. It covers traditional anticoagulants such as low molecular weight heparins, warfarin, as well as new anticoagulants like argatroban, rivaroxaban, apixaban and direct thrombin inhibitors dabigatran etexilate. This paper also looks forward to future novel anticoagulants using dabigatran etexilate as a lead compound.
Keywords :
drugs; anticoagulants; apixaban; argatroban; dabigatran etexilate; heparins; rivaroxaban; synthesis methods; warfarin; Atrial fibrillation; Blood; Compounds; Degradation; Drugs; Inhibitors; Raw materials; anticoagulant; research; synthesis;
Conference_Titel :
Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
Conference_Location :
Macau, Macao
Print_ISBN :
978-1-4577-1987-5
DOI :
10.1109/iCBEB.2012.441
