Title :
Interaction Motifs in Regulatory Networks and Structural Robustness
Author :
Elena, A. ; Demongeot, J.
Author_Institution :
Fac. of Med. of Grenoble, Univ. J. Fourier, Grenoble
Abstract :
If we consider the regulatory networks used in systems biology, we observe certain regularities in their architecture, namely the occurrence of interaction motifs, i.e. of oriented sub-graphs relating their elements with the same interaction scheme. We propose to describe some of these universal motifs and to study their main dynamical properties especially concerning their robustness (called also structural stability), i.e. their ability to keep after topological or dynamical perturbations, their essential asymptotic features, as their attractors number, shape and behavior, like their periodicity.
Keywords :
biology; interaction motif; regulatory network; structural robustness; structural stability; systems biology; Competitive intelligence; Electronic mail; Genetics; Intelligent networks; Intelligent structures; Robust stability; Robustness; Software systems; Structural engineering; Systems biology; attractors; interaction motifs; periodicity; regulatory networks; robustness; structural stability;
Conference_Titel :
Complex, Intelligent and Software Intensive Systems, 2008. CISIS 2008. International Conference on
Conference_Location :
Barcelona
Print_ISBN :
978-0-7695-3109-0
DOI :
10.1109/CISIS.2008.31