DocumentCode :
2683075
Title :
Numerical Simulation of Descending Curves Sinusoidal Microchannel for Cell Separation System
Author :
Ashraf, Muhammad Waseem ; Tayyaba, Shahzadi ; Ishaque, Muhammad ; Afzulpurkar, Nitin
Author_Institution :
Sch. of Eng. & Technol., Asian Inst. of Technol. (AIT), Bangkok, Thailand
fYear :
2012
fDate :
28-30 May 2012
Firstpage :
1070
Lastpage :
1073
Abstract :
This paper deals with a new design of cell separation system. The presented system consists of focusing channel, cell separation device, micro pump, fluid flow sensor, sample storage unit, electronic circuit, central processing unit (CPU), micro controller, cell storage unit and drain collection unit. Finite element software has been used for numerical simulation of descending curves micro channel. The diameters of micro channel curves are 50 μm, 45 μm, 40 μm, 35 μm, 30 μm. Solid particles have been modeled in the channel to analyze the inertial effects during fluid-solid interaction. The diameter of each solid particle is 5 μm. The channel width is 15 μm. The driving pressure of 50 to 300 kPa has been applied on the inlet of micro channel to push the fluid through channel. The inertial forces on the particles inside the channel have been investigated. Presented system and micro channel design can be used for bacterial detection in the blood.
Keywords :
bioMEMS; biosensors; cellular biophysics; computational fluid dynamics; finite element analysis; flow sensors; microchannel flow; microcontrollers; microfabrication; micropumps; microsensors; separation; bacterial detection; blood; cell separation device; cell separation system; cell storage unit; central processing unit; descending curves sinusoidal microchannel; drain collection unit; electronic circuit; finite element software; fluid flow sensor; fluid-solid interaction; inertial effects; microcontroller; micropump; numerical simulation; pressure 50 kPa to 300 kPa; sample storage unit; size 5 mum to 50 mum; solid particles; Fluids; Focusing; Microchannel; Numerical simulation; Solids; Sorting; Cell separation system; Computational fluid dynamic (CFD); Microchannels; Microfluidics;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
Conference_Location :
Macao
Print_ISBN :
978-1-4577-1987-5
Type :
conf
DOI :
10.1109/iCBEB.2012.285
Filename :
6245312
Link To Document :
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