Silicon Nanowire Based Immunoassay for the Detection of Prostate Cancer Biomarkers

Author

Lee, Min-Ho ; Seong, Wookyeong ; Lee, Sangdae ; Kim, Kyungsik

Author_Institution

Med. IT Convergence Center, Korea Electron. Technol. Inst., Seongnam, South Korea

fYear

2012

fDate

28-30 May 2012

Firstpage

1086

Lastpage

1088

Abstract

Recent reports of nanowire based biosensor research showed the promising ability in detection time less than one minute and in detection level down to pg/ml to list a few. In this study, we used newly modified top down based silicon nanowire and measured two types of prostate cancer markers after surface modification. Their dynamic ranges were measured to be 0.184 ~ 17 ng/mL and 0.1 ~ 10 ng/mL, respectively.

Keywords

biosensors; cancer; chemical sensors; elemental semiconductors; nanofabrication; nanomedicine; nanowires; patient diagnosis; proteins; semiconductor quantum wires; surface treatment; IL-6 antibodies; PSA antibodies; SiNW FET sensor; detection level; detection time; nanowire based biosensor; prostate cancer biomarker detection; prostate specific antigen antibodies; silicon nanowire based immunoassay; surface modification; Fabrication; Immune system; Microfluidics; Nanobioscience; Proteins; Semiconductor device measurement; Silicon; IL-6; PSA; prostate cancer; silicon nanowire;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on

Conference_Location

Macau, Macao

Print_ISBN

978-1-4577-1987-5

Type

conf

DOI

10.1109/iCBEB.2012.352

Filename

6245316