Title :
Double lock-in concept for MORE glucose detection
Author :
Jang, Sunghoon ; Fox, Martin D.
Author_Institution :
Dept. of Electr. & Syst. Eng., Connecticut Univ., Storrs, CT, USA
Abstract :
We previously proposed a new approach to optical glucose sensing based on the fact that glucose solutions have a magnetic optical rotatory effect (MORE). The proportionality with the glucose concentration was found to be linear with single and double MORE at physiologic concentrations. Use of MORE has a number of potential advantages over the conventional optical rotatory effect including improved spatial resolution and sensitivity. We introduce the concept of using double lock-in amplifiers to separate a small, narrow band signal from interfering noise in this study
Keywords :
Faraday effect; biomedical electronics; biosensors; chemical sensors; feedback amplifiers; laser applications in medicine; magneto-optical sensors; measurement by laser beam; polarimeters; Faraday effect; MORE glucose detection; double lock-in amplifiers; glucose concentration; improved sensitivity; improved spatial resolution; interfering noise; magnetic optical rotatory effect; narrow band signal; optical glucose sensing; polarimeter; Conductors; Mirrors; Optical amplifiers; Optical filters; Optical noise; Optical polarization; Optical reflection; Optical sensors; Stimulated emission; Sugar;
Conference_Titel :
Bioengineering Conference, 1999. Proceedings of the IEEE 25th Annual Northeast
Conference_Location :
West Hartford, CT
Print_ISBN :
0-7803-5486-9
DOI :
10.1109/NEBC.1999.755792
