Title :
Secondary Bjerknes forces deform targeted microbubbles
Author :
Kokhuis, Tom J. A. ; Naaijkens, B.A. ; Juffermans, Lynda J. M. ; Kamp, Otto ; Versluis, Michel ; de Jong, Nico
Author_Institution :
Biomedical Engineering, Thorax Center, Erasmus MC, Rotterdam, the Netherlands
Abstract :
Secondary Bjerknes forces can rupture the binding of targeted microbubbles. We have shown before that this effect can be used to quantify the adhesion strength between bubble and target surface [1]. At lower pressures however, microbubbles were observed to snap back to their original position within 100 µs after ultrasound application. In this study the mechanism of this restoring force was investigated in more detail using simultaneous top and side view high speed imaging [2]. Moreover, some results on the process of microbubble detachment (peeling versus uniform rupture) are presented.
Keywords :
Acoustics; Adhesives; Biomedical imaging; Educational institutions; Force; Ultrasonic imaging; acoustic radiation force; bubble deformation; microbubble detachment; secondary Bjerknes force; targeted microbubbles;
Conference_Titel :
Ultrasonics Symposium (IUS), 2012 IEEE International
Conference_Location :
Dresden, Germany
Print_ISBN :
978-1-4673-4561-3
DOI :
10.1109/ULTSYM.2012.0167