DocumentCode
2691960
Title
A comparison study on protein-protein interaction network models
Author
Mingyu Shao ; Yi Yang ; Jihong Guan ; Shuigeng Zhou
Author_Institution
Sch. of Comput. Sci., Fudan Univ., Shanghai, China
fYear
2012
fDate
4-7 Oct. 2012
Firstpage
1
Lastpage
4
Abstract
This paper presents a comprehensive comparison study on the performances of major existing models over two PPI datasets, by comparing the global and local statistical properties of the original PPI networks and the model-reproduced ones. Our experimental results show that the DD model has best fitting ability while iSite model and STICKY model also fit well with the PPI datasets over most statistical properties.
Keywords
bioinformatics; biological techniques; molecular biophysics; proteins; statistical analysis; DD model; PPI datasets; STICKY model; iSite model; protein-protein interaction network models; statistical properties; Analytical models; Bioinformatics; Biological system modeling; Data models; Electronics packaging; Proteins; Biological mechanism; FFl network models; Performance comparison; Statistical properties;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine (BIBM), 2012 IEEE International Conference on
Conference_Location
Philadelphia, PA
Print_ISBN
978-1-4673-2559-2
Electronic_ISBN
978-1-4673-2558-5
Type
conf
DOI
10.1109/BIBM.2012.6392732
Filename
6392732
Link To Document