Title :
A comparison study on protein-protein interaction network models
Author :
Mingyu Shao ; Yi Yang ; Jihong Guan ; Shuigeng Zhou
Author_Institution :
Sch. of Comput. Sci., Fudan Univ., Shanghai, China
Abstract :
This paper presents a comprehensive comparison study on the performances of major existing models over two PPI datasets, by comparing the global and local statistical properties of the original PPI networks and the model-reproduced ones. Our experimental results show that the DD model has best fitting ability while iSite model and STICKY model also fit well with the PPI datasets over most statistical properties.
Keywords :
bioinformatics; biological techniques; molecular biophysics; proteins; statistical analysis; DD model; PPI datasets; STICKY model; iSite model; protein-protein interaction network models; statistical properties; Analytical models; Bioinformatics; Biological system modeling; Data models; Electronics packaging; Proteins; Biological mechanism; FFl network models; Performance comparison; Statistical properties;
Conference_Titel :
Bioinformatics and Biomedicine (BIBM), 2012 IEEE International Conference on
Conference_Location :
Philadelphia, PA
Print_ISBN :
978-1-4673-2559-2
Electronic_ISBN :
978-1-4673-2558-5
DOI :
10.1109/BIBM.2012.6392732
