Title :
Novel method and device for viscoelastic tissue characterization of edema
Author :
Kruger, Grant H. ; Dodde, R.E. ; Koziol, Leo B. ; Weitzel, William F.
Author_Institution :
Dept. of Mech. Eng., Univ. of Michigan, Ann Arbor, MI, USA
Abstract :
Quantitative evaluation of tissue hydration and edema is a key marker to guide clinical care. Towards this end, a pulsed-wave (PW) tissue Doppler device to directly measure time-dependent tissue deformation (strain and strain rate) is being developed. With integrated bio-impedance (BIZ) measurements, this system has the potential to significantly improve the edema assessments currently being used. The current study acquires depth dependent tissue creep Doppler signals which are fitted to a linear viscoelastic model to obtain time constants suitable for assessing edema. In addition BIZ measurements were performed looking forward to sensor integration. Work continues to advance the determination of viscoelastic tissue properties, targeting the prototype development for clinical studies.
Keywords :
biological tissues; biomechanics; biomedical equipment; creep; deformation; diseases; internal stresses; patient care; viscoelasticity; BIZ measurements; PW tissue Doppler device; bioimpedance measurements; clinical care; depth dependent tissue creep Doppler signals; edema; linear viscoelastic model; prototype development; pulsed-wave tissue Doppler device; quantitative evaluation; sensor integration; strain rate; time-dependent tissue deformation; tissue hydration; viscoelastic tissue characterization; Creep; Doppler effect; Mathematical model; Phantoms; Strain; Strain measurement; Ultrasonic variables measurement; Bioimpedance; Edema; Tissue Doppler;
Conference_Titel :
Ultrasonics Symposium (IUS), 2012 IEEE International
Conference_Location :
Dresden
Print_ISBN :
978-1-4673-4561-3
DOI :
10.1109/ULTSYM.2012.0592
