DocumentCode
269768
Title
Nucleosides analogues recognition by molecularly imprinted polymer-coated Love wave sensor
Author
Lebal, N. ; Hallil, H. ; Dejous, C. ; Plano, B. ; Krstulja, A. ; DelepeÌe, R. ; Agrofoglio, L. ; RebieÌ€re, D.
Author_Institution
IMS Lab., Bordeaux Univ., Talence, France
Volume
8
Issue
10
fYear
2013
fDate
Oct. 2013
Firstpage
563
Lastpage
566
Abstract
Presented is a process for thin film molecularly imprinted polymer (MIP) coating based on commercial nucleotides adenosine monophosphate (AMP). The compatibility of the MIP film with acoustic propagation and sensor sensitivity for rebinding of AMP have been verified. Thin and porous layers of AMP-based MIP layers were successfully deposited on the sensor surface. Detection tests of AMP have been performed in aqueous media. The sensor response was recorded in terms of frequency and total insertion losses after both steps: AMP extraction from MIP then AMP rebinding. The sensor showed high sensitivity to 25 ppm AMP concentration. The effect of the extraction time on rebinding capacity of the MIP layer has been proven.
Keywords
Love waves; acoustic devices; acoustic wave propagation; biomedical equipment; coatings; polymer films; porous materials; thin film sensors; AMP concentration; AMP rebinding; AMP-based MIP layers; MIP film; acoustic propagation; acoustic sensor; adenosine monophosphate; aqueous media; molecularly imprinted polymer-coated Love wave sensor; nucleotides; porous layers; rebinding capacity;
fLanguage
English
Journal_Title
Micro & Nano Letters, IET
Publisher
iet
ISSN
1750-0443
Type
jour
DOI
10.1049/mnl.2013.0207
Filename
6651445
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