DocumentCode
2713878
Title
A dual-excitation difference technique for fluorescence rejection in Raman spectroscopy
Author
Cai, Zhijian ; Zou, Wenlong ; Wu, Jianhong
Author_Institution
Inst. of Inf. Opt. Eng., Soochow Univ., Suzhou, China
fYear
2011
fDate
3-5 Nov. 2011
Firstpage
29
Lastpage
32
Abstract
Fluorescence disturbance is the primary limiting factor of biomedical Raman spectroscopy. This paper proposed a dual-excitation difference technique for fluorescence rejection. In this research, a low-cost dual-excitation system was built for Raman detection, and a robust deconvolution algorithm was developed for spectrum recovery. Simulation and experimental results demonstrated that this method could effectively eliminate the fluorescence background in Raman spectroscopy.
Keywords
Raman spectra; bio-optics; deconvolution; fluorescence; medical signal processing; Raman detection; biomedical Raman spectroscopy; dual-excitation difference technique; fluorescence background elimination; fluorescence disturbance; fluorescence rejection; robust deconvolution algorithm; spectrum recovery; Deconvolution; Fluorescence; Laser excitation; Noise; Raman scattering; Signal processing algorithms; Spectroscopy;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioelectronics and Bioinformatics (ISBB), 2011 International Symposium on
Conference_Location
Suzhou
Print_ISBN
978-1-4577-0076-7
Type
conf
DOI
10.1109/ISBB.2011.6107637
Filename
6107637
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