A hardware implementation of real-time epileptic seizure detector on FPGA

A considerable portion of epilepsy cannot be well treated by today´s available therapies. Brain stimulation with closed-loop seizure control was recently proposed. In our previous work, high accuracy of seizure controller (92-99% during wake-sleep states) using a microcontroller has been proposed and implemented to verify functionality of seizure detection and suppression on a freely moving rat. In this paper, the soft intellectual property (IP) of epileptic seizure detector in the implantable system on chip (SoC) for epileptic seizure control is proposed to achieve continuous real-time processing and low power consumption. All the essential macros for epileptic seizure detector are implemented and integrated in field programmable gate array (FPGA) to verify functionality and capability. The evaluation results of the prototype supported possible application of a portable and continuous real-time seizure control.