Title :
Wide bandwidth cell impedance spectroscopy based on digital auto balancing bridge method
Author :
Li, Nan ; Xu, Hui ; Zhou, Zhou ; Sun, Zhaolin ; Xu, Xin ; Wang, Wei
Author_Institution :
Sch. of Electron. Sci. & Eng., Nat. Univ. of Defense Technol., Changsha, China
Abstract :
This paper presented the design of a cell impedance spectroscopy which based on a digital auto balancing bridge method. The hardware architecture of the system mainly consists of a reference source, a variable source, a null detector and a FPGA. DSP algorithms such as CORDIC-based direct digital synthesis and LMS-based auto balancing algorithm were discussed in detail. The simulation results show that the system has good performance from low frequency up to 10 MHz. Profiting from the cost efficiency and high flexibility of digital device, it suitable for EIS application in cell-level research.
Keywords :
bioelectric potentials; biomedical electronics; biomedical engineering; cellular biophysics; digital signal processing chips; electric impedance; electric impedance imaging; field programmable gate arrays; least mean squares methods; medical computing; CORDIC based direct digital synthesis; DSP algorithm; FPGA; LMS based auto balancing algorithm; cell level research; digital auto balancing bridge method; digital device; electrical impedance spectroscopy; hardware architecture; least mean square algorithm; null detector; wide bandwidth cell impedance spectroscopy; Algorithm design and analysis; Bridge circuits; Computer architecture; Field programmable gate arrays; Frequency measurement; Impedance; Microprocessors;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2011 IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
978-1-4577-1469-6
DOI :
10.1109/BioCAS.2011.6107725
