A State Space Model for the Long Term Blood Pressure Regulation

This paper presents a linear state variable description of the long term arterial blood pressure regulation, developed for the analysis of the system properties. The influence of model parameters on the stability and dynamic behavior is analyzed using system theory concepts. The eigenvalues under normal and diseased states have been evaluated through root locus techniques, which could provide clinical applications of prediction and diagnosis. The results obtained through numerical solution showed that the model is able to reproduce responses which are close to those of the actual nonlinear model.