Title :
Compressed sensing for digital holographic microscopy
Author :
Marim, Marcio M. ; Atlan, Michael ; Angelini, Elsa D. ; Olivo-Marin, J.-C.
Author_Institution :
CNRS, Inst. Pasteur, Paris, France
Abstract :
This paper describes an original microscopy imaging framework successfully employing Compressed Sensing for digital holography. Our approach combines a sparsity minimization algorithm to reconstruct the image and digital holography to perform quadrature-resolved random measurements of an optical field in a diffraction plane. Compressed Sensing is a recent theory establishing that near-exact recovery of an unknown sparse signal is possible from a small number of non-structured measurements. We demonstrate with practical experiments on holographic microscopy images of cerebral blood flow that our CS approach enables optimal reconstruction from a very limited number of measurements while being robust to high noise levels.
Keywords :
biomedical optical imaging; blood flow measurement; brain; holography; image reconstruction; medical image processing; minimisation; neurophysiology; optical microscopy; sparse matrices; cerebral blood flow; compressed sensing; diffraction plane; digital holographic microscopy; image reconstruction; near-exact recovery; noise levels; nonstructured measurements; optical field; original microscopy imaging framework; quadrature-resolved random measurements; sparse signal; sparsity minimization algorithm; Compressed sensing; Holographic optical components; Holography; Image reconstruction; Microscopy; Minimization methods; Optical diffraction; Optical imaging; Optical sensors; Performance evaluation; Compressed Sensing; biological microscopy; digital holography; signal reconstruction;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on
Conference_Location :
Rotterdam
Print_ISBN :
978-1-4244-4125-9
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2010.5490084