Integrated Fluorescence Sensing for Lab-on-a-chip Devices

Author

Ji, Honghao ; Dandin, Marc ; Abshire, Pamela ; Smela, Elisabeth

Author_Institution

Dept. of Electr. Eng., Maryland Univ., College Park, MD

fYear

2006

fDate

38899

Firstpage

1

Lastpage

2

Abstract

A low noise optical sensor and biocompatible microscale optical filters for integrated fluorescence sensors were developed and tested. The sensor was fabricated in a 0.5 mum CMOS process. The measured reset noise of the sensor is reduced by a factor of 10 compared to conventional active pixel sensors. The transmission ratio in the pass-band and suppression ratio in the stop-band of the optical filters are comparable to that of macroscopic commercial filters for fluorescence microscopy

Keywords

CMOS integrated circuits; bioMEMS; biological techniques; biosensors; fluorescence; lab-on-a-chip; microsensors; optical filters; optical sensors; 0.5 mum; CMOS; biocompatible microscale optical filters; fluorescence microscopy; fluorescence sensors; integrated fluorescence sensing; lab-on-a-chip devices; low noise optical sensor; pass-band; stop-band; suppression ratio; transmission ratio; Biosensors; CMOS process; Fluorescence; Lab-on-a-chip; Noise measurement; Optical filters; Optical microscopy; Optical noise; Optical sensors; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Life Science Systems and Applications Workshop, 2006. IEEE/NLM

Conference_Location

Bethesda, MD

Print_ISBN

1-4244-0277-8

Electronic_ISBN

1-4244-0278-6

Type

conf

DOI

10.1109/LSSA.2006.250392

Filename

4015793