Effects of Light Waveforms on a Circadian Oscillation of Clock Genes

Author

Tsumoto, Kunichika ; Kurosawa, Gen ; Aihara, Kazuyuki

Author_Institution

Inst. of Industrial Sci., Tokyo Univ.

fYear

2006

fDate

38899

Firstpage

1

Lastpage

2

Abstract

For studying autonomous circadian rhythms of proteins in organisms, various mathematical models have been proposed. In this study, we have investigated bifurcations of periodic oscillations observed in circadian models incorporating the effect on a light-dark cycle and show that the waveform of the periodic variation in the light-induced parameter has a marked influence on the global bifurcation structure or the type of dynamic behavior resulting from the forcing term of the circadian oscillator by the LD cycles

Keywords

biological effects of optical radiation; circadian rhythms; genetics; molecular biophysics; oscillations; physiological models; proteins; autonomous circadian rhythms; circadian oscillation; clock genes; global bifurcation structure; light waveform effects; light-dark cycle; mathematical models; periodic oscillations; proteins; Bifurcation; Circadian rhythm; Clocks; Degradation; Laboratories; Mathematical model; Organisms; Oscillators; Periodic structures; Proteins;

fLanguage

English

Publisher

ieee

Conference_Titel

Life Science Systems and Applications Workshop, 2006. IEEE/NLM

Conference_Location

Bethesda, MD

Print_ISBN

1-4244-0277-8

Electronic_ISBN

1-4244-0278-6

Type

conf

DOI

10.1109/LSSA.2006.250395

Filename

4015796