Title :
Image registration of whole-body mouse MRI
Author :
Chen, X. Josette ; Maheswaran, Satheesh ; Ruckert, Daniel ; Henkelman, R. Mark
Author_Institution :
Hosp. for Sick Children, Toronto, ON, Canada
Abstract :
We registered together 13 whole-body MR images of perfusion-fixed mice. Twelve organs in a single mouse were then manually segmented and the labels were propagated to the other mice. Registration performance was evaluated both visually and by averaging the volumes of the individual organs across the mice. We have found an excellent tool for rapidly phenotyping organs in whole body mouse images.
Keywords :
biological organs; biomedical MRI; image registration; image segmentation; medical image processing; image registration; perfusion-fixed mice; phenotyping organs; whole body mouse images; whole-body MRI; Animal structures; Biological system modeling; Heart; Hospitals; Image registration; Image segmentation; Lungs; Magnetic resonance imaging; Mice; Ultrasonic imaging; MRI; phenotyping; registration; whole mouse;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on
Conference_Location :
Rotterdam
Print_ISBN :
978-1-4244-4125-9
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2010.5490174