Title :
Why multiple b-values are required for multi-tensor models. evaluation with a constrained log-euclidean model
Author :
Scherrer, Benoit ; Warfield, Simon K.
Author_Institution :
Dept. of Radiol., Comput. Radiol. Lab., Boston, MA, USA
Abstract :
Multi-tensor models have been proposed to assess multiple fiber orientations but are known to be numerically challenging. We show that the estimation cannot be performed with a single-shell HARDI acquisition because the fitting procedure leads to an infinite number of solutions ; multiple-shell HARDI acquisitions are required. Additionally, we propose a new log-euclidean constrained two-tensor model capable of assessing crossing fibers configurations with a relative limited number of DW acquisitions. We provide numerical experiments with this model to verify experimentally the necessity of multiple-shell HARDI acquisitions schemes for multitensor models.
Keywords :
Gaussian distribution; biomedical MRI; brain; image resolution; neurophysiology; phantoms; DW acquisition; b-value; constrained log-euclidean model; crossing fiber configuration; diffusion MRI; fiber orientation; multiple-shell HARDI acquisition; multitensor model; single-shell HARDI acquisition; two-tensor model; Anisotropic magnetoresistance; Diffusion tensor imaging; High-resolution imaging; Hospitals; Humans; Image resolution; Laboratories; Magnetic resonance imaging; Radiology; Tensile stress; Diffusion MRI; b-value; logeuclidean; two-tensor model;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on
Conference_Location :
Rotterdam
Print_ISBN :
978-1-4244-4125-9
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2010.5490257