Regularized multilevel B-spline registration: Application to cardiac motion estimation

In this paper, we propose a new method for image registration based on multilevel b-splines. We improve the transformation estimation by introducing some constraints in the general scheme that regularize the grid of control points. Our method is computationally effective and results in smooth transformations that are representative of the motion between the images. Comparative results are presented on ultrasound image registration to estimate the motions of the cardiac walls.