Parametric imaging in dynamic susceptibility contrast MRI-phantom and in vivo studies

Author

Ruminski, J. ; Bobek-Billewicz, B.

Author_Institution

Dept. of Biomed. Eng., Gdansk Univ. of Technol., Poland

Volume

1

fYear

2004

fDate

1-5 Sept. 2004

Firstpage

1104

Lastpage

1107

Abstract

Possibility of quantitative perfusion imaging with DSC MRI is still under discussion. In this work, the quantitative related parameters are analyzed and DSC-MRI limitations are discussed. It includes investigation of measurement procedures/conditions as well as parametric image synthesis methodology. The set of phantoms was constructed and used to inspect the role of Gd-DTPA concentration estimation by EPI measurements, the influence of partial volume effect on concentration estimation, the role of a phantom and its pipes orientation, etc. Additionally, parametric image synthesis methodology was investigated by analysis of influence of a bolus dispersion, bolus arrival time, and other signal parameters on an image quality. As a conclusion testing software package is proposed.

Keywords

biomedical MRI; biomedical measurement; chemical variables measurement; haemorheology; organic compounds; phantoms; software packages; EPI measurement; Gd-DTPA concentration estimation; bolus dispersion; dynamic susceptibility contrast MRI-phantom; echo planar imaging; image quality; parametric imaging; partial volume effect; quantitative perfusion imaging; testing software package; Image analysis; Image generation; Image quality; Imaging phantoms; In vivo; Magnetic resonance imaging; Signal analysis; Software packages; Software testing; Volume measurement; DSC MRI; parametric imaging; phantom studies;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE

Conference_Location

San Francisco, CA

Print_ISBN

0-7803-8439-3

Type

conf

DOI

10.1109/IEMBS.2004.1403357

Filename

1403357