Computer Based Karyotyping

Karyotyping is a fundamental step in chromosome analysis. Since G-banding patterns of any chromosomes in the metaphase spread are changeable, it is difficult and time consuming for students to master the technique of karyotyping. Current methods for leaning karyotyping are ineffective, and therefore it is necessary to develop a software program to help students learn the skill efficiently. Virtual reality is suitable for this purpose because of its inherent simulating ability. By building dynamic chromosome models capable changing shapes, G-band resolutions, and structure, along with creating variable metaphase spreads, a versatile software program was developed to provide students with a virtual learning environment for self practicing and testing, thus transforming the traditionally dry and tedious approach into an exciting and efficient learning process.