Title :
The development of biosensor with imaging ellipsometry
Author :
Jin, G. ; Zhao, Z.-Y. ; Wang, Z.-H. ; Meng, Y.-H. ; Ying, P.-Q. ; Chen, S. ; Chen, Y.-Y. ; Qi, C. ; Xia, L.-H.
Author_Institution :
Chinese Acad. of Sci., Beijing, China
Abstract :
The concept of biosensor with imaging ellipsometry was proposed about ten years ago. It has become an automatic analysis technique for protein detection with merits of label-free, multi-protein analysis, and real-time analysis for protein interaction process, etc. Its principle, and related technique units, such as micro-array, micro-fluidic and bio-molecule interaction cell, sampling unit and calibration for quantitative detection as well as its applications in biomedicine field are presented here.
Keywords :
biosensors; ellipsometry; microfluidics; molecular biophysics; patient diagnosis; proteins; biomedical applications; biomolecule interaction cell; biosensor; calibration; imaging ellipsometry; label-free multi-protein analysis; micro-array; microfluidic; protein detection; real-time protein interaction process analysis; sampling unit; Biosensors; Calibration; Ellipsometry; Face detection; Optical imaging; Protein engineering; Sampling methods; Silicon; Surface treatment; Visualization; Biosensor; imaging ellipsometry; micro-array;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1403583
