Computer simulation of stress analysis in benzocyclobutene (BCB) based neural interface

Computer simulation was performed using finite element analysis (FEA) to analyze stress profile in a neural probe made of benzocyclobutene (BCB) polymer with a thin silicon backbone layer. The probe is made up of three distinct sections. Sections 1 and 2 have a silicon backbone layer on the BCB to provide adequate stiffness required for easy handling during surgery (insertion and fixation), while section 3 is totally flexible. The simulation results indicate that the stress points are always buildup on the interface of stiff sections 1 and 2. The probe is more likely to fail at these interface points during handling if bending occurs. Increasing the length of section 1 significantly lowers the stress level. Further, 5 μm silicon backbone layer depicted lower stress level, in the present design.