Title :
Modeling and Control of Electroporation-Mediated Gene Delivery
Author :
Zhang, Mingjun ; Ou Ma
Author_Institution :
Biomed. Eng. Program, Tennessee, Univ., Knoxville, TN
Abstract :
This paper proposes a model and control strategies for the electroporation - mediated gene-delivery based on chemo-electro-mechanical model of the process. Simulation results demonstrate the effectiveness of the proposed strategies.
Keywords :
biochemistry; bioelectric potentials; biomechanics; cellular biophysics; drug delivery systems; genetics; medical control systems; nanobiotechnology; chemoelectromechanical model; control strategies; electroporation; gene delivery; Biological system modeling; Biomembranes; DNA; Equations; Mathematical model; Process control; Simulation;
Conference_Titel :
Nanotechnology, 2008. NANO '08. 8th IEEE Conference on
Conference_Location :
Arlington, TX
Print_ISBN :
978-1-4244-2103-9
DOI :
10.1109/NANO.2008.252
