Title :
Flexible neural probes with micro-fluidic channels for stable interface with the nervous system
Author :
Suzuki, T. ; Ziegler, D. ; Mabuchi, K. ; Takeuchi, S.
Author_Institution :
Graduate Sch. of Inf. Sci. & Technol., Tokyo Univ., Japan
Abstract :
A flexible neural probe with micro-fluidic channels has been developed. The probe is sufficiently flexible to enable minimally invasive recording. The fluidic channel integrated on the probe is capable of injecting chemicals into neural tissues. In addition, it permits a stable interface with the nervous system. We focus on issues concerning: 1) stable recording with electrodes placed in fluidic channels, 2) improved mechanical stiffness by filling channels with a solid that dissolves in neural tissues, and 3) the probe´s application to a nerve regeneration electrode.
Keywords :
biological tissues; biomedical electrodes; microfluidics; neurophysiology; chemical injection; flexible neural probes; improved mechanical stiffness; microfluidic channels; minimally invasive recording; nerve regeneration electrode; nervous system; neural tissues; stable recording; Biological materials; Control systems; Electrodes; Fabrication; Humans; Microfluidics; Nervous system; Neural prosthesis; Probes; Silicon; BMI; Parylene; flexible neural probe; micro-fluidic channel; nerve regeneration electrode;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1404132