Title :
A bio-amplifier with pulse output
Author :
Du Chen ; Harris, John G. ; Principe, Jose C.
Author_Institution :
Dept. of Electr. & Comput. Eng., Florida Univ., Gainesville, FL, USA
Abstract :
A low-power fully integrated bioamplifier is presented that can amplify signals in the range from mHz to kHz while rejecting large DC offsets generated at the electrode-tissue interface. The novel aspect of this amplifier is that its analog output is represented by a series of pulses which provide a low-power, noise-resistant means for coding and transmission. The original analog signal can be reconstructed from the resulting pulse train with 13 bit precision at a remote site where power consumption is not so crucial. The fabricated analog amplifier exhibits a gain of 39.5 dB from 0.3 Hz to 5.4k Hz. The power consumption of the whole system is less than 300 μW/channel from a 5-V supply. The fully integrated system was designed in the AMI 0.6 μm CMOS process and it consumes 0.088 mm2/channel of chip area.
Keywords :
CMOS analogue integrated circuits; bioelectric phenomena; biological tissues; biomedical electrodes; brain; microelectrodes; neurophysiology; pulse amplifiers; 0.3 to 5.4 Hz; 39.5 dB; 5 V; CMOS process; bio-amplifier; electrode-tissue interface; low-power fully integrated bioamplifier; low-power noise-resistant coding; low-power noise-resistant transmission; pulse output; Biomedical electrodes; CMOS process; Circuit noise; Energy consumption; Extracellular; Neurons; Preamplifiers; Pulse amplifiers; Pulse circuits; Signal processing; : Bio-amplifier; CMOS; low power; pulse train;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1404136
