Wireless multichannel biopotential recording using an integrated FM telemetry circuit

This paper reports on the design, implementation, and testing of wireless multichannel recording microsystems featuring on-chip AC amplification, DC input stabilization, time-division-multiplexing, and wireless FM reconstruction of input biopotentials with frequency contents from 0.05-6kHz with measured I/O correlation coefficients in the range of 70-94% per channel for spike train input amplitudes of 0.2-2mV_p-p while dissipating only 2.2 mW from 3 V. The 4.84 mm² IC is fabricated using AMI 1.5 μm 2P2M CMOS process, and is successfully interfaced with a micromachined silicon probe for simultaneous multichannel wireless in vitro recording of simulated neural spikes at 98MHz with measured I/O correlation coefficients of >80%.